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Our research program is focussed on both the fundamental and applied aspects of self-assembly and molecular recognition in water. We are pursuing chemical strategies to control polymer, peptide and lipid assemblies to target biomedical problems and achieve controlled chemical delivery in vivo. Each research effort begins with molecular design and organic synthesis, though the final application of these synthetic systems is in cell culture or animal models, which we interrogate both independently and through collaboration with researchers at the OSU Medical Center and OSU Comprehensive Cancer Center. |
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About the group: Research in the group is highly multidisciplinary: projects begins with organic synthesis and branch into biophysics, bioanalytical studies, cell biology and in vivo studies. Researchers with these diverse backgrounds work together to investigate molecular recognition at synthetic and cellular membranes and how this recognition event may be elaborated into membrane chemistry. To this end, our group pursues research in the design and organic synthesis of simple but potentially biologically interesting lipids, peptides, polymers and membrane assemblies. |