1. Li, X.*; Fekner, T.*; Chan, M.K., “N6-(2-(R)-Propargylglycyl)lysine as a clickable pyrrolysine mimic”,  Chemistry – an Asian Journal, 2010, 5, 1765-9. 

  2. Fekner, T.; Li, X.; Chan, M.K., “Towards pyrrolysine analogs for site-specific modification of proteins”, Eur J Org Chem., 2010, 4171-4179. 

  3. Li, X.*; Fekner, T.*; Ottesen, J.J.; Chan, M.K., “A pyrrolysine analog for site-specific protein ubiquitination”, Angew. Chem., 2009, 48, 9184-7. 

  4. Lee, M.M.*; Isaza, C.E.*; White, J.D.; Chen, R.P.-Y.; Liang, G.F.-C.; Chan, S.I.; Chan, M.K., “Structural basis for the substrate length restriction in M32 carboxypeptidases: evidence for a distinct class of M32 carboxypeptidase”, Proteins, 2009, 77, 647-657. 

  5. Lee, M.M.; Chan, M.K.; Bundschuh, R., “SIB-BLAST: a web server for improved delineation of true and false positives in PSI-BLAST searches”, Nucleic Acids Res., 2009, 37, W53-6. 

  6. Fekner, T.*; Li, X.*; Lee, M.M.; Chan, M.K., “A pyrrolysine analog for protein click chemistry” Angew. Chem., 2009, 48, 1633-5. 

  7. Li, W.-T.; Mahapatra, A.; Longstaff, D.G.; Bechtel, J.; Zhao, G.; Kang, P.T.; Chan, M.K.; Krzycki, J.A., “Specificity of pyrrolysyl-tRNA synthetase for pyrrolysine and pyrrolysine analogs” J. Mol. Biol., 2009, 385, 1156-64. 

  8. Lee, M.M.; Jiang, R.; Jain, R.; Larue, R.C.; Krzycki, J.A.; Chan, M.K., “Structure of Desulfitobacterium hafniense PylSc, a pyrrolysyl tRNA synthetase” Biochem. Biophys. Res. Commun. 2008, 374, 470-4. 

  9. Isaza, C.E.; Zhong, X.; Rosas, L.E.; White, J.D.; Chen, R.P.-Y.; Liang, G.F.-C.; Chan, S.I.; Satoskar, A.R.; Chan, M.K., “Leishmania major carboxypeptidase: a proposed role in pathogens” Biochem. Biophys. Res. Commun. 2008, 373, 25-9. 

  10. Gong, W.*; Hao, B.*; Wei, Z.; Ferguson, D.J. Jr.; Tallant, T.; Krzycki, J.A.; Chan, M.K., “Structure of the CODH component of the M. barkeri ACDS complex” Proc. Natl. Acad. Sci. USA 2008, 105, 9558-63. 

  11. Lee, M.M.; Chan, M.K.; Bundschuh, R., “Simple is beautiful: a straightforward approach to improve the delineation of true and false positives in PSI-BLAST searches” Bioinformatics, 2008, 24, 1339-43.  

  12. Lee, M.M.; Bundschuh, R.; Chan, M.K., “Distant homology detection using a LEngth and STructure-based sequence Alignment Tool (LESTAT)” Proteins 2008, 71, 1409-19. 

  13. Li, X.; Jayachandran, S.; Nguyen, H.H.-T; Chan, M.K. “Structure of the Nitrosomonas europaea Rh protein” Proc. Natl. Acad. Sci. USA 2007, 104, 19279-19284. 

  14. Jain, R.; Chan, M.K., “Support for a potential role of E. coli oligopeptidase A in protein degradation”, Biochem. Biophys. Res. Commun. 2007, 359, 486-90. 

  15. Mahapatra, A.; Srinivasan, G.; Richter, K.B.; Meyer, A.; Lienard, T.; Zhang, J.K.; Zhao, G., Kang, P.T.; Chan, M.; Gottschalk, G.; Metcalf, W.W.; Krzycki, J.A., “Class I and class II lysyl-tRNA synthetase mutants and the genetic encoding of pyrrolysine in Methanosarcina spp.” Mol Microbiol. 2007, 64, 1306-18. 

  16. Chan, S.I.; Wang, V.C.-C.; Lai, J.C.-H.; Yu, S.S.-F.; Chen, P.P.-Y.; Chen, K.H.-C.; Chen, C.-L.; Chan, M.K., “Redox potentiometry studies of particulate methane monooxygenase: Support for a trinuclear copper cluster active site” Angew. Chem. Int. Ed., 2007, 46, 992-4. 

  17. Isaza, C.E.; Silaghi-Dumitrescu, R.; Iyer, R.B.; Kurtz, Jr, D.M.; Chan, M.K, “Structural basis for O2 sensing by the hemerythrin-like domain of a bacterial chemotaxis protein: substrate tunnel and fluxional N-terminus” Biochemistry, 2006, 45, 9023-31. 

  18. Jain, R.; Hao, B.; Liu, R.P.; Chan, M.K., “Structures of E. coli peptide deformylase bound to formate: insight into the preference for Fe2+ over Zn2+ as the active site metal” J. Am. Chem. Soc., 2005, 127, 4558-9. 

  19. Hao, B.*; Zhao, G.*; Kang, P.T.; Soares, J.A.; Ferguson, T.K.; Gallucci, J.; Krzycki, J.A.; Chan, M.K.; “Reactivity and chemical synthesis of L-pyrrolysine - the 22nd genetically-encoded amino acid” Chem. Biol., 2004, 11, 1317-24. (cited in C&E News) 

  20. Blight, S.K.; Larue, R.C., Mahapatra, A., Longstaff, D.G., Chang, E. Zhao, G., Kang, P., Green-Church, K.B., Chan, M.K., Krzycki, J.A., “Direct charging of tRNACUA with pyrrolysine in vitro and in vivo” Nature, 2004, 431, 333-5. (cited in Nature, C&E News) 

  21. Arndt, J.W.; Chen, K.H.-C.; Zhong, X.; Krzycki, J.A.; Chan, M.K. “Support for nickel as the labile metal in the A-center of the M. barkeri acetyl-CoA decarbonylase/synthase complex” J. Chin. Chem. Soc., 2004, 51, 1253-1258. 

  22. Chan, S.I.; Chan, M.K. “Archaean thermostable carboxypeptidases” in Handbook of Proteolytic Enzymes (2nd Edition),  2004,  1,  778-781. 

  23. Fekner, T., Gallucci, J, Chan., M.K., “Synthesis and metalation of a chiral, pyridine-strapped, cyclic bis(benzimidazole) ligand” Org. Lett.,  2004, 6, 989-92. (Org. Lett., hot article) 

  24. Fekner, T., Gallucci, J, Chan., M.K., “Ruffling-induced chirality: synthesis, metallation, and optical resolution of highly non-planar, cyclic benzimidazole-based ligands” J. Am. Chem.  Soc., 2004, 126, 223-36. 

  25. Fekner, T., Gallucci, J, Chan., M.K., “Intramolecular aromatic nucleophilic substitution of the benzimidazole-activated nitro group” Org. Lett.,  2003, 5, 4795-8. 

  26. Zhong, X., Hao, B., Chan, M.K., “Structure of the PAS fold and signal transduction mechanisms” in PAS Proteins: Regulators and Sensors of Development and Physiology, Crews, S. Ed., 2003, Kluwer Publishing, New York, NY. 

  27. Jain, R. Chan, M.K., “Mechanisms of ligand discrimination by heme proteins” JBIC, 2003, 8, 1-11. 

  28. Hao, B., Gong, W., Ferguson, T.K., James, C.M., Krzycki, J.A., Chan, M.K., “Identification of novel UAG encoded residue: structure of a methanogen methyltransferase” Science, 2002, 296, 1462-1466. (cited in C&E News, Nature, Science, CNN Headline News, Reuters) 

  29. Hao, B., Isaza, C., Arndt, J., Soltis, M., Chan, M.K., “Structural analysis of the mechanism of oxygen sensing by the FixL heme domain of Bradyrhizobium japonicum” Biochemistry, 2002, 41, 12952-12958. 

  30. Arndt, J.W., Hao, B., Ramakrishnan, V., Chen, T., Chan, S. I., Chan,, M.K., “Structure of the hyperthermophilic Pyrococcus furiosus carboxypeptidase” Structure, 2002, 10, 215-224. 

  31. Payra, P. Hung, S.-C., Kwok, W.-H., Johnston, D. Gallucci, J., Chan, M.K., “Structural, magnetic and catalytic properties of a self-recognized -oxo-bridged diiron(III) bis(benzimidazole) complex“ Inorg. Chem., 2001, 40, 4036-4039. 

  32. Arndt, J.W., Gong, W., Zhong, X., Liu, J., Lin, Z., Schowalter, A.K., Paxson, C., Tsai, M.-D., Chan, M.K., “Insight into the catalytic mechanism of DNA polymerase : structures of intermediate complexes” Biochemistry, 2001, 40, 5368- 5375. 

  33. Chan, M.K., “Recent advances in heme-protein biosensors” Curr. Opin. Chem. Biol., 2001, 5, 216-222. 

  34. Chan, M.K.“CooA,CAP and allostery” Nat. Struct. Biology, 2000, 7, 822-824. 

  35. Kwok, W.H., Zhang, H., Payra, P., Duan, M., Hung, S.-C., Johnston, D.H., Gallucci, J., Skrzypczak-Jankun, E., Chan, M.K., “Synthesis and characterization of the dimethyl-substituted bisbenzimidazole ligand and its manganese complex” Inorg. Chem., 2000, 39, 2367-2376. 

  36. Chan, M. K., “Symposium overview: heme protein biosensors” J. Porphyrins. Phthalocyanines, 2000, 4, 358-361. 

  37. Gong, W., Hao, B., Chan, M.K., “New mechanistic insights from structural studies of the oxygen-sensing domain of Bradyrhizobium japonicum FixL” Biochemistry, 2000, 3955-3962. 

  38. Payra, P., Kwok, W.H., Zhang, H., Payra, P., Duan, M., Gallucci, J., Chan, M.K. “Structural trends in first row transition-metal bisbenzimidazole complexes” Inorg. Chem., 2000, 39, 1076-1080. 

  39. Hao, B., Gong, W., Rajagopalan, P.T.R., Zhou, Y., Pei, D., Chan. M.K., “Structural basis for the design of antibiotics targeting peptide deformylase” Biochemistry, 1999, 38, 4712-4719. 

  40. Randall, D. W., Chan, M. K., Armstrong, W. H., and Britt, R. D., “Pulsed 1H and 55Mn ENDOR studies of dinuclear Mn(III)Mn(IV) model complexes” Mol. Phys., 1998, 95, 1283-1294. 

  41. Gong, W.*, Hao, B.*, Mansy, S.S., Gonzalez, G. Gilles-Gonzalez, M.A., Chan, M.K., “Structure of a biological oxygen sensor: a new mechanism for heme-driven signal transduction” Proc. Natl. Acad. Sci. USA, 1998, 95, 15177-15182. 

  42. Chan, M.K., Gong, W., Rajagopalan, P.T.R., Hao, B., Tsai, C.M., Pei, D., “Crystal structure of the Escherichia coli peptide deformylase” Biochemistry, 1997, 36, 13904-13909. 

  43. Randall, D.W., Sturgeon,B.E., Ball,J.A., Lorigan,G.A., Chan, M.K., Klein,M.P.,  Armstrong,W.H., Britt, R.D., “Mn-55 ESE-ENDOR of a mixed-valence Mn(III)Mn(IV) complex - comparison with the Mn cluster of the photosynthetic oxygen-evolving complex” J. Am. Chem. Soc., 1995, 117, 11780-11789. 

  44. Kletzin, A., Mukund, S., Kelleycrouse, T.L., Chan, M.K., Rees, D.C., Adams, M.W.W., “Molecular characterization of the genes encoding the tungsten-containing aldehyde ferredoxin oxidoreductase from Pyrococcus-furiosus and formaldehyde ferredoxin oxidoreductase from Thermococcus-litoralis” J. Bacteriology, 1995, 177, 4817-4819. 

  45. Chan, M.K., Mukund, S., Kletzin, A., Adams, M.W.W., Rees, D.C., “The 2.3Å resolution structure of the tungstoprotein aldehyde ferredoxin oxidoreductase from the hyperthermophilic archaeon Pyrococcus furiosus” Science, 1995, 267, 1463-1469. 

  46. Rees, D.C., Chan, M.K.;,Kim, J., “Structure and Function of Nitrogenase” in Advances in Inorganic  Chemistry,  Vol. 40.; A.G. Sykes Ed.; Academic Press, Inc., San Diego, California, 1994, p. 89. 

  47. Chan, M.K., Kim, J., Rees, D.C., “The nitrogenase FeMo-cofactor and P-cluster pair: 2.2 Å resolution structures” Science, 1993, 260, 792-794. 

  48. Rees, D.C., Kim, J., Georgiadis, M., Chan, M.K., Komiya, H., Woo, D., Chirino, A.J., Schlessman, J.,  Hsu, B.T., “Structures and Functions of the Nitrogenase Proteins” in New Horizons in Nitrogen  Fixation; Palacios, R., Mora, J., Newton, W.E., Eds.; Kluwer Academic Publishers, Dordrecht, the  Netherlands, 1993, p. 83.      

  49. Rees, D.C., Kim,J., Georgiadis, M.M., Komiya, H., Chirino,A.J., Woo, D., Schlessman, J., Chan,  M.K., Joshua-Tor,L., Santillan, G., Chakrabarti, P., Hsu, B.T., “Crystal-Structures of the Iron Protein  and Molybdenum Iron Protein of Nitrogenase” in Molybdenum Enzymes, Cofactors, and Model Systems,  ACS Symposium Series  535, Stiefel, E.I., Coucouvanis, D., Newton, W.E. Eds., American Chemical  Society, Washington D.C., 1993;  p. 170. 

  50. Kirk, M.L., Chan, M.K., Armstrong, W.H., Solomon, E.I., “Ground-state electronic structure of the dimer-of-dimers complex [(Mn2O2)2(tphpn)2]4+: Potential relevance to the photosystem II water oxidation catalyst” J. Am. Chem. Soc., 1992, 114, 10432-10440. 

  51. Pal, S.; Chan, M.K., Armstrong, W.H. “Ground spin state variability in manganese oxo aggregates.  Demonstration of an S=3/2 ground state for [Mn3O4(OH)(bpea)3] (ClO4)3”,J.  Am. Chem. Soc., 1992, 114, 6398-6406. 

  52. Cramer, S.P., deGroot, F.M.F., Ma, Y., Chen, C.T., Sette, F., Kipke, C.A., Eichhorn, D.M., Chan, M.K., Armstrong, W.H., Libby, E., Christou, G., Brooker, S., McKee, V., Mullins, O.C.,  Fuggle, J.C. “Ligand field strengths and oxidation states from manganese L-edge spectroscopy” J. Am. Chem.  Soc., 1991, 113, 7937. 

  53. Chan, M.K., Armstrong, W.H. “A tetranuclear manganese complex that consists of a di-alkoxo-bridged dimer of di-oxo-bridged dimers, [(Mn2O2)2(tphpn)2}4+. Toward a model for the water oxidation catalyst in photosystem II”,J. Am. Chem. Soc., 1991, 113, 5055-5057. 

  54. Chan, M.K., Armstrong, W.H. “A tetranuclear manganese-oxo complex with a 2.7 Å Mn•••Mn separation and intramolecular H2O•••(2-O) hydrogen-bonded contacts: [Mn4O2(TPHPN)2(H2O)2(CF3SO3)2](CF3SO3)3. Possible mode for binding of water at the active site of the oxygen-evolving complex in photosystem II” J. Am. Chem. Soc., 1990, 112, 4985-4986. 

  55. Chan, M.K., Armstrong, W.H. “A novel tetranuclear manganese complex that displays multiple high-potential redox processes. Synthesis, structure, and properties of {[Mn2(TPHPN)(O2CCH3)2(H2O)]2O}(ClO4)4•2CH3OH” J. Am. Chem. Soc., 1989, 111, 9121-9122. 

  56. Dexheimer, S.L., Ghodes, J.W., Chan, M.K., Hagen, K.S., Armstrong, W.H., Klein, M.P. “Detection of EPR spectra in S=2 states of trivalent manganese complexes” J. Am. Chem. Soc., 1989, 111, 8923-8925. 

  57. Chan, M.K., Armstrong, W.H. “A high-potential mononuclear manganese(IV) complex. Synthesis, structure, and properties, including EPR spectroscopy and electrochemistry, of [Mn(HB(3,5-Me2pz)3)2](ClO4)2” Inorg. Chem., 1989, 28, 3777-3779. 

  58. Kubota, M.K., Chan, M.K., Boyd, D.C., Mann, K.R. “Thermal and photolytic reactions of nitrosyl-carbonyl complexes of rhodium and iridium with triphenylphosphine” Inorg. Chem., 1987, 26, 3261-3264. 

  59. Kubota, M.K., Chan, M.K., Woo, L.K. “Iridium-Nitrogen bond cleavage in the photolysis of carbonylnitrosylbis(triphenylphosphine)iridium” Inorg. Chem., 1984, 23, 1636-1638.