~ the gopalan group ~

Dr. Venkat Gopalan, Ph.D.

Education and Training
1992-1997*	Postdoctoral work at Yale University, New Haven, Connecticut, USA (Mentor: Dr. Sidney Altman) *Also, a visiting scholar for brief periods at the MRC Laboratory of Molecular Biology, Cambridge, UK (Mentor: Sir Aaron Klug)
1991	Ph.D. (Biochemistry) University of New Mexico, Albuquerque, New Mexico, USA (Mentor: Dr. Robert H. Glew)
1986	B.Sc. (Chemistry) University of Madras, Madras, INDIA


Positions Held
2003 to date	Associate Professor, Department of Biochemistry, OSU
2000 to date	Adjunct Faculty, Department of Plant Biology, OSU
1998 - 2003	Assistant Professor, Department of Biochemistry, OSU


Honors and Awards
2008	2007-2008 OSU Harlan Hatcher Memorial Award for Excellence
2005	OSU College of Biological Sciences 2005 Dean's Award for Excellence in Classroom Teaching
2003-2004	Outstanding Teaching Award Finalist Presented by the Arts and Sciences Colleges Student Council
2003	OSU College of Biological Sciences 2003 Dean's Award for Undergraduate Research Mentoring
1995-1996	Postdoctoral Fellow of the Anna Fuller Cancer Research Fund
1993-1995	Postdoctoral Fellow of the Patrick and Catherine Donaghue Medical Research Foundation





Past Publications
Gopalan, V., Kuhne, H., Biswas, R., Li, H., Brudvig, G. W. and Altman, S. (1999) Mapping RNA-protein interactions in ribonuclease P from Escherichia coli using electron paramagnetic resonance spectroscopy. Biochemistry 38: 1705-1714.
Gopalan, V., Golbik, R., Schreiber, G., Fersht, A. and Altman, S. (1997) Fluorescence properties of a tryptophan residue in an aromatic core of the protein subunit of ribonuclease P from Escherichia coli. J. Mol. Biol. 267: 765-769.
Gopalan, V., Baxevanis, A., Landsman, D. and Altman, S. (1997) Analysis of the functional role of conserved residues in the protein subunit of ribonuclease P from Escherichia coli. J. Mol. Biol. 267: 818-829.
Gopalan, V., Talbot, S. J., and Altman, S. (1994) RNA-protein interactions in RNase P. In RNA-Protein Interactions - Frontiers in Molecular Biology (Nagai, K., and Mattaj, I., Eds.), pp. 103-126, Oxford University Press, Oxford, UK.
Glew, R. H., Gopalan, V., Forsyth, G. W., and Vander Jagt, D. J. (1993) The mammalian cytosolic broad-specificty ß-glucosidase. In Biochemistry and Molecular Biology of ?-Glucosidases (Esen, A., Ed.), pp. 83-112, American Chemical Society, Washington, D.C.
Gopalan, V., Pastuszyn, A., Galey, W. R., Jr., and Glew, R. H. (1992) Exolytic hydrolysis of toxic plant glucosides by guinea pig liver cytosolic ß-glucosidase. J. Biol. Chem. 267: 14027-14032.
Gopalan, V., Vander Jagt, D. J., Libell, D. P., and Glew, R. H. (1992) Transglucosylation as a probe of the mechanism of action of mammalian cytosolic ß-glucosidase. J. Biol. Chem. 267: 9629-9638.
Lai, L. B., Gopalan, V., and Glew, R. H. (1992) Continuous spectrophotometric assays for ´-glucosidases acting on the plant glucosides L-picein and prunasin. Anal. Biochem. 200: 365-369.
Glew, R. H., Gopalan, V., Hubbell, C.A., Devraj, R. V., Lawson, R. A., Diven, W. F., and Mannock, D. A. (1991) 2,3-Di-O-tetradecyl-1-O-(ß-D-glucopyranosyl)-sn-glycerol is a substrate for human glucocerebrosidase. Biochem. J. 274: 557-563.
Glew, R. H., Gopalan, V., Hubbell, C. A., Beutler, E., Geil, J. D., and Lee, R. E. (1991) A case of non-neurologic Gaucher's disease that resembles the neurologic type biochemically. J. Neuropathol. Exp. Neurol. 50: 108-117.
Butcher, B. A., Gopalan, V., Lee, R. E., Richards, T. C., Waggoner, A. S., and Glew, R. H. (1989) Use of 4-heptylumbelliferyl-ß-D-glucoside to identify Gaucher's disease heterozygotes. Clin. Chim. Acta 184: 235-242.
Gopalan, V., Glew, R. H., Libell, D. P., and DePetro, J. J. (1989) The dual effects of alcohols on the kinetic properties of guinea pig liver cytosolic ß-glucosidase. J. Biol. Chem. 264: 15418-15422.
Gopalan, V., Daniels, L. B., Glew, R. H., and Claeyssens, M. (1989) Kinetic analysis of the interaction of alkyl glycosides with two human ß-glucosidases. Biochem. J. 262: 541-548.