Claudia Turro received her B.S. with Honors in 1987 from Michigan State University. She worked with Daniel G. Nocera and George E. Leroi at Michigan State University and received her Ph.D. in 1992. She was awarded a Jane Coffin Childs Memorial Fund for Medical Research Postdoctoral Fellowship to conduct postdoctoral work at Columbia University with Nicholas J. Turro (no relation) from 1992 to 1995, and has been a faculty member at The Ohio State University since 1996. She received the Early CAREER Award by the National Science Foundation in 1998, the Arnold and Mabel Beckman Foundation Young Investigator Award in 1999, was named a 2010 Fellow of the American Chemical Society (ACS), and a 2012 Fellow of the American Association for the Advancement of Science. She was elected President of the Inter-American Photochemical Society (2012-14) and Chair of the ACS Division of Inorganic Chemistry (2016). She received the 2014 College of Arts and Sciences Susan M. Hartmann Mentoring and Leadership Award, the 2014 Award in Photochemistry from the Inter-American Photochemical Society, the 2016 Edward W. Morley Medal from the Cleveland Section of the ACS, and the 2016 Award of the Columbus Section of the ACS. Since 2016, she has been serving as Associate Editor for the Journal of the American Chemical Society.
Inorganic Photochemistry, Excited State Processes, Solar Energy Conversion, Photochemotherapy
The Turro group is interested in understanding and utilizing reactions of metal complexes that can be initiated with light. The potential applications of these reactions span the areas of photochemotherapy (PCT) for the treatment various diseases, luminescent reporters and sensors, degradation of pollutants triggered by light, and solar energy conversion. In order to improve and expand their reactivity, the fundamental understanding of the excited states of mononuclear and dinuclear metal-metal bonded transition metal complexes is necessary and remains an important subject of investigation. This work is currently funded by the National Science Foundation. The work in the Turro group investigates the control and dynamics of excited states, including photophysical properties, and reactivity, including energy transfer, charge separation and charge recombination, and photochemical reactions. Understanding and controlling these processes is vital for numerous applications, including solar energy conversion, photochemotherapy, and sensing. Transition metal complexes that are nontoxic in the dark and become highly toxic upon irradiation with visible or near-IR light are ideal for PCT. Complexes that undergo photo-induced ligand dissociation are under investigation, such that the complex can deliver drugs or inhibitors that selectively target tumors, while simultaneously producing reactive oxygen species to induce cancer cell death. This work is currently supported by the National Institutes of Health. The Turro group has also discovered new materials that are able to both harvest photons and undergo catalytic transformations to produce clean fuels. This work is currently funded by the Department of Energy.
Recent Selected Publications
Knoll, J. D.; Turro, C. “Control and Utilization of Ruthenium and Rhodium Metal Complex Excited State for Photoactivated Cancer Therapy” Coord. Chem. Rev. 2015, 282-283, 110-126.
Palmer, A. M.; Knoll, J. D.; Turro, C. “Photinduced Interactions of Two Dirhodium Complexes with d(GTCGAC)2 Probed by 2D NOESY” Invited paper for themed issue on “Interactions of Metal Complexes with Nucleic Acids”, Dalton Trans. 2015, 44, 3640-3646.
Knoll, J. D.; Albani, B. A.; Turro, C. “Excited State Investigation of New Ru(II) Complex for Dual Reactivity with Low Energy Light” Chem. Commun. 2015, 51, 8777-8780.
Knoll, J. D.; Albani, B. A.; Turro, C. “New Ru(II) Complexes for Dual Reactivity: Ligand Exchange and 1O2 Generation” Acc. Chem. Res. 2015, 48, 2280-2287.
Tu, Y.-J.; Mazumder, S.; Endicott, J. F.; Turro, C.; Kodanko, J. J.; Schlegel, H. B. “Selective Photodissociation of Acetonitrile Ligands in Ruthenium Polypyridyl Complexes Studied by Density Functional Theory” Inorg. Chem. 2015, 54, 8003-8011.
White, T. A.; Witt, S. E.; Li, Z.; Dunbar, K. R.; Turro, C. “A New Rh2(II,II) Architecture for the Catalytic Reduction of H+” Inorg. Chem. 2015, 54, 10042-10048.
Albani, B. A.; Peña, B.; Saha, S.; White, J. K.; Schaeffer, A. M.; Dunbar, K. R.; Turro, C. "A Dinuclear Ru(II) Complex Capable of Photoinduced Ligand Exchage at Both Metal Centers" Chem. Comm. 2015, 51, 16522-16525.
White, T. A.; Dunbar, K. R.; Thummel, R. P.; Turro, C. "Electronic Influences of Bridging and Chelating Diimine Ligand Coordination in Formamidinate-Bridged Rh2(II,II) Dimers", invited paper for special issue dedicated to Malcolm H. Chisholm, Polyhedron 2016, 103, 172-177.
Li, A.; White, J. K.; Arora, K.; Herroon, M.; Martin, P. D.; Schlegel, H. B.; Podgorski, I.; Turro, C.; Kodanko, J. J. "Selective Release of Aromatic Heterocycles from Ruthenium Tris(2-pyridylmethyl)amine with Visible Light", Inorg. Chem. 2016, 55, 10-12.
Loftus, L. M.; White, J. K.; Albani, B. A.; Kodanko, J. J.; Thummel, R. P.; Dunbar, K. R.; Turro, C. "Excited State Deactivation of a New Ru(II) Complex by Multiple Pathways", Chem. Eur. J., 2016, 22, 1-6.
Herroon, M. K.; Sharmak, R.; Rajagurbandara, E.; Turro, C. Kodanko, J. J.; Podgorski, I. "Photoactivated Inhibition of Cathepsin K in a 3D Tumor Model", Biol. Chem. 2016, 397, 571-582.
Arora, K.; Sharma, R.; White, J. K.; Mazumder, S.; Martin, P. D.; Schlegel, H. B.; Turro, Claudia; Kodanko, J. J. "Effects of Methyl Substitution in Ruthenium Tris(2-pyridinemethyl)amine Photocaging Groups for Nitriles" Inorg. Chem. 2016, 55, 6968-6979.
Witt, S. E.; White, T. A.; Li, Z.; Dunbar, K. R.; Turro, C. "Cationic Dirhodium(II,II) Complexes for the Electrocatalytic Reduction of CO2 to HCOOH" Chem. Commun. 2016, 52, 12175-12178.
Huisman, M.; White, J. K.; Lewalski, V. G.; Podgorski, I.; Turro, C., Kodanko, J. M. "Caging the Uncageable: Using Metal Complex Release for Photochemical Control over Irreversible Inhibition" Chem. Commun. 2016, 52, 12590-12593.
White, J. K.; Schmehl, R. H.; Turro, C. "An Overview Of Photosubstitution Reactions Of Ru(II) Imine Complexes And Their Application In Photobiology And Photodynamic Therapy", invited paper for special issue dedicated to Karen Brewer, Inorg. Chim. Acta 2017, 454, 7-20.
Akhimie, R. N.; White, J. K.; Turro, C. "Dual Photoreactivity of a New Rh2(II,II) Complex for Biological Applications", invited paper for special issue dedicated to Karen Brewer, Inorg. Chim. Acta 2017, 454, 149-154.