Organic Chemistry

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Ohio State has a rich history of intellectual breakthroughs that have laid the foundation for advancement and discovery in modern organic chemistry. The culture of innovation continues today, with innovative research thrusts across the frontiers of organic synthesis, chemical biology, biotechnology and materials, powered by a thriving community of advisers, postdoctoral scientists, graduate and undergraduate students.

Research Areas

  • Catalysis
  • Chemical biology
  • Computational chemistry
  • Drug design and delivery
  • Energy and fuels
  • Nanoscience and nanotechnology
  • Organic materials
  • Organic synthesis
  • Natural products
  • Physical organic chemistry
  • Supramolecular chemistry

 

Faculty

Advanced
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Jovica Badjic

Jovica Badjic

My group focuses on developing novel synthetic hosts for trapping molecules and promoting chemical reactions.

  • Physical Organic Chemistry
  • Supramolecular Chemistry
  • Nanoscience & Nanotechnology

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Dennis Bong

Dennis Bong

We design and synthesize polymer, peptide, lipid and nucleic acid constructs to achieve controlled chemical delivery in vivo. Research efforts begin with chemistry and trace a path through biophysical, biochemical and cell culture studies.

  • Chemical Biology
  • Drug Delivery
  • Biomaterials

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Craig Forsyth

Craig Forsyth

Synthesis of complex, biologically active organic molecules based upon natural product templates; enabling synthetic methods; selective protein serine-threonine inhibition; mechanism of action of the phorboxazole, thyrsiferyl, and apratoxin natural products

  • Organic Synthesis
  • Natural Products
  • Chemical Biology

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Christopher Hadad

Christopher Hadad

Biochemical applications in which organic transformations occur in an enzyme's active site; reactive oxygen species and reactive intermediates in biochemical, atmospheric (environmental) and combustion environments; catalysts for improved conversion of chemical feedstocks

  • Physical Organic Chemistry
  • Computational Chemistry
  • Energy & Fuels

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Psaras McGrier

Psaras McGrier

Research in the McGrier group focuses on utilizing novel synthetic methods to create functional porous and polymeric materials that can be useful for environmental safety, device applications, and clean energy technologies.

  • Organic Materials
  • Microporous & Mesoporous Materials
  • Photochemistry

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David Nabig

David Nagib

Developing multi-faceted approaches for selective C-H and C-O activation, using combinations of radical (1e-) and closed shell (2e-) processes.

  • Organic Synthesis
  • Catalysis
  • C-H Activation

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Jon Parquette

Jon Parquette

Our research revolves around the theme of organic nanotechnology. We focus on the synthesis and assembly of organic nanomaterials that function as catalysts, optoelectronics, biomedical materials and drug delivery vectors.

  • Organic Materials
  • Nanoscience & Nanotechnology
  • Catalysis

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Dehua Pei

Dehua Pei

Discovery and delivery of macrocyclic compounds as chemical probes and therapeutics against protein-protein interactions; delivery of proteins and nucleic acids into mammalian cells

  • Chemical Biology
  • Bioorganic & Medicinal Chemistry
  • Biotechnology

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T. V. (Babu) RajanBabu

T. V. (Babu) RajanBabu

Major areas of our research are in the development new catalytic enantioselective methods  for C-C, C-H and C-N bond formations using readily available organic precursors and catalysts, and, applications of the newly developed methods for the synthesis of biologically relevant molecules.

  • Organic Synthesis
  • C-C Coupling
  • Catalysis

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Christo Sevov

Christo Sevov

Our research targets the development of new strategies for safe, sustainable, and scalable organic synthesis and energy storage that exist at the interface of homogeneous catalysis and electrochemistry.

  • Organic Synthesis
  • Catalysis
  • Energy & Fuels