Courses

A survey of biochemistry stressing the qualitative rather than the quantitative approach. Credit does not count toward a major in biochemistry. Prereq: Chem 1110 (102) or 1210 (122), or equiv. Not open to students with credit for 211 and 212.

Introduction to biochemical research through seminars and laboratory tours by faculty in the department. Biology 1113 (113) recommended but not required. Prereq: Honors standing, and Chem 1220 (123), 1620 (163), or 1920H (203H); or permission of instructor. Not open to students with credit for 1900H or 200H. This course is graded S/U.

A laboratory sequel to Biochem 2900H to introduce undergraduates to biochemical research. Prereq: Honors standing, and 2900H; or permission of instructor. Not open to students with credit for 1998H or 201H. This course is graded S/U.

An introductory course in biochemistry dealing with the molecular basis of structure, metabolism, genetic replication, transcription, and translation in plants, animals, and microorganisms. Prereq: Chem 1220, 1250, 1620, or 1920H, and 2510, 2310, 2610, or 2910H and one semester of Biological Sciences.

An introductory course in biochemistry and molecular biology developing in three semesters the molecular basis of structure and function of living cells. Prereq: Chem 2510 (252), 2610, or 2910H. Prereq or concur: Chem 2520 (253), 2620, or 2920H, and one semester in Biological Sciences. Not open to students with credit for 613 or 4511 (511).

Continuation of Biochem 5613. Prereq: A grade of C- or above in 5613.

Continuation of Biochem 5614. Prereq: A grade of C- or above in 5614.

Laboratory course covering the principles and application of basic lab techniques, protein purification, enzyme assays, and recombinant DNA technologies. Prereq: A grade of C- or above in 4511 or 5613, or equiv.

Introduction to physical chemistry with emphasis on biological applications; designed for students in the life sciences. Prereq: Biology 1113; Math 1152 (153), 1172, 1181H, or 2162 (162); and Physics 1201 (113) or 1251 (133). Prereq or concur: Chem 2520 (253), 2620, or 2920H. Not open to students with credit for 721.01 or Chem 4200 or 4300.

Continuation of Biochem 5721. Prereq: 5721, or Chem 4200 or 4300. Not open to students with credit for 721.02 and 721.03.

The course will examine the dilemma that we face in our modern world of attempting to balance the great benefits of modern chemical sciences and technology with the risks that accompany those benefits, through the lens of chemicals that have changed the world around us. This course includes a laboratory experience. Prereq: Math 1050, or an ACT math subscore of 22 or higher that is less than two years old, or satisfactory score on Ohio State Math Placement Test. Not open to students with credit for 1100, 1110, 1210, 1610, 1910H, or any Chem course that uses these courses as prerequisites.

Introductory chemistry for non-science majors, including dimensional analysis, atomic structure, bonding, chemical reactions, states of matter, solutions, chemical equilibrium, acids and bases, along with topics in organic and biological chemistry. Prereq: Math 1073, 1074, 1075 or above; Math Placement Level L, M, N, or R; or ACT Math subscore of 22 or higher that is less than 2 years old. Not open to students with credit for 1210, 1250, 1610, or 1910H.

Chem 1206 is the first course in a two-course series, for science majors, covering units & measurement, atomic structure, electron configuration, periodic trends, bonding, and molecular structure. The chemistry content is covered in the same depth and rigor as in Chem 1210, and is about 1/2 of the Chem 1210 content. Additionally, metacognitive learning strategies are taught in the course. Prereq or concur: Math Placement Level L or M, Math 1120, 1130, 1131, 1140, 1148, 1150, or above. Not open to students with credit for 1210, 1220, 1610, 1620, 1910H, 1920H, 1250.

CHEM 1208 is second course in a two-course series, for science majors, covering the mole, stoichiometry, chemical reactions, thermochemistry, gases, liquids, and solids, paired with metacognitive learning strategies. CHEM 1208 also includes a laboratory experience, that covers labs from both CHEM 1206 and CHEM 1208 content. Credit for CHEM 1206 and CHEM 1208 is equivalent to CHEM 1210. Prereq: Chem 1206, and a grade of C- or above in Math 1120, 1130, 1131, 1140, 1148, 1150, or above. Not open to students with credit for 1210, 1220, 1610, 1620, 1910H, 1920H, 1250.

First course for science majors, covering dimensional analysis, atomic structure, the mole, stoichiometry, chemical reactions, thermochemistry, electron configuration, bonding, molecular structure, gases, liquids, and solids. Prereq: One unit of high school chemistry, and Math Placement Level L or M; or a grade of C- or above in Math 1120, 1130, 1131, 1148, 1150, or above. Not open to students with credit for 1220, 1620, 1920H, 1250, 1610, or 1910H.

Continuation of 1210 for science majors, covering solutions, kinetics, chemical equilibrium, solubility and ionic equilibria, qualitative analysis, thermodynamics, electrochemistry, descriptive chemistry, coordination compounds, and nuclear chemistry. Prereq: 1210, 1215, 1250, 1610, or 1910H, and Math Placement Level L or M, or a grade of C- or above in Math 1120, 1130, 1131, 1148, or 1150, or above; or credit for both Chem 1206 and 1208.

First course for engineering majors, covering dimensional analysis, atomic and molecular structure, the mole, stoichiometry, chemical reactions, states of matter, solutions, kinetics, equilibrium, acids and bases, thermodynamics, and electrochemistry. Prereq: One unit of high school chemistry; and Math Placement Level L or M, or a grade of C- or above in Math 1120, 1130, 1131, 1148, or 1150, or above. Not open to students with credit for 1210, 1610, 1910H, 2310, 2510, 2610, or 2910H.

First course for chemistry and biochemistry majors, covering dimensional analysis, atomic structure, the mole, stoichiometry, chemical reactions, thermochemistry, electron configuration, bonding, molecular structure, gases, liquids, and solids. Prereq: One unit of high school chemistry, and Math Placement Level L or M; or a grade of C- or above in Math 1120, 1130, 1131, 1148, or 1150, or above, and enrolled in Chemistry or Biochemistry major; or permission of department. Not open to students with credit for 1210, 1220, 1250, 1620, 1910H, or 1920H.

Continuation of 1610 for science majors, covering solutions, kinetics, chemical equilibrium, solubility and ionic equilibria, qualitative analysis, thermodynamics, electrochemistry, descriptive chemistry, coordination compounds, and nuclear chemistry. Prereq: 1210, 1215, 1250, 1610, or 1910H; and a grade of C- or above in Math 1120, 1130, 1131, 1148, or 1150, or above, or Math Placement Level L or M; and enrollment in Chemistry or Biochemistry major; or permission of department. Not open to students with credit for 1220, 1920H, 2310, 2510, 2610, or 2910H.

Fundamental chemical principles and the chemistry of nonmetals for selected students. Prereq: ACT composite score of 30 or above, and ACT mathematics score of 30 or above, and ACT science reasoning score of 28 or above. Prereq or concur: Math 1141 or 1151 or above, or permission of instructor. Not open to students with credit for 1210 or 1610.

Continuation of Chem 1910H for selected students covering fundamental principles and the chemistry of metals. Prereq: 1910H (202H). Not open to students with credit for 203H, 1220 or 1620.

Quantitative chemical analysis for chemistry majors; quantitative analysis of the elemental and molecular composition of complex systems. Prereq: 1220 (123), 1620 (163), or 1920H (203H), and Math Placement Level L, or a grade of C- or above in Math 1148 and 1149, or 1130 (130), 1131 (131), or 1150 (150), or above. Not open to students with credit for 2210H (221H).

Honors version of quantitative chemical analysis for chemistry majors; quantitative analysis of the elemental and molecular composition of complex systems. Prereq: Honors standing, or permission of department or instructor; and 1220 (123), 1620 (163), or 1920H (203H), and Math Placement Level L, or a grade of C- or above in Math 1148 and 1149, or 1130 (130), 1131(131), or 1150 (150), or above. Not open to students with credit for 2210 (221).

A condensed presentation of organic chemistry organized by functional groups with an emphasis on practical applications. Prereq: 1110, 1220 (122), 1250 (125), 1620, or 1920H. Not open to students with credit for 2510 (251), 2610, or 2910H.

Introduction to structure, nomenclature, physical properties, preparation and reactions of alkanes, alkenes, conjugated dienes, alkynes, alcohols, ethers, epoxides, aldehydes, and ketones. Other topics include stereochemistry, conformations of molecules, acids, bases, and reaction mechanisms. Prereq: Chem 1208, or 1210, or 1250, or 1610 or 1910H; and Chem 1220, or 1620 or 1920H; and Math Placement Level L or M, or a grade of C- or above in Math 1120, 1130, 1131, 1148, 1150, or above. Not open to students with credit for Chem 2520, 2610, 2620, 2910H, or 2920H.

Continuation from 2510, including aromatic systems, carboxylic acids, carboxylic acid derivatives, amines, carbon-carbon bond-forming reactions, polymers, carbohydrates, and amino acids. Prereq: Chem 1208, 1210, 1250, 1610, or 1910H, and Chem 1220, 1620, or 1920H, and Chem 2510, 2610, or 2910H, and Math Placement Level L or M, or a grade of C- or above in Math 1120, 1130, 1131, 1148, 1150, or above. Not open to students with credit for Chem 2620 or 2920H.

Introduction to spectroscopic characterization, scientific writing, computational chemistry, and the laboratory techniques of organic chemistry, including synthesis, isolation, purification, and identification of organic compounds. Spectroscopic techniques discussed included (Infrared Spectroscopy, Mass Spectrometry, 1H and 13C Nuclear Magnetic Resonance). Prereq or concur: 2310, or 2510, or 2610 or 2910H; and 1208, or 1210, or 1250, or 1610 or 1910H; and 1220, or 1620 or 1920H; and Math Placement Level L or M, or a grade of C- or above in Math 1120, 1130, 1131, 1148, 1150, or above.

Synthetic application to various organic reaction and spectroscopic characterization, scientific writing, computational chemistry, and the laboratory techniques of organic chemistry. The course includes application of synthesis, isolation, purification, and identification of organic compounds. Continued discussion of techniques and problem solving related to spectroscopy. Prereq or concur: Chem 2520, 2620 or 2920H; and prereq: Chem 1208, 1210, 1250, 1610 or 1910H; and 1220, 1620 or 1920H; and 2510, 2610 or 2910H; and 2540; and Math Placement Level L or M or a grade of C- or above in Math 1120, 1130, 1131, 1148, 1150 or above.

Introduction to structure, nomenclature, physical properties, preparation and reactions of alkanes, alkenes, alkynes, alcohols, ethers, epoxides, aldehydes and ketones. Other topics include stereochemistry, acids, bases, and reaction mechanisms. Prereq: 1220 (123), 1620 (163), or 1920H (203H); and Chemistry or Biochemistry major, or permission of Department. Not open to students with credit for 252.

Continuation from 2610, including aromatic systems, carboxylic acids, carboxylic acid derivatives, amines, carbon-carbon bond-forming reactions, polymers, carbohydrates and amino acids. Prereq: 2510 (252), 2610, or 2910H; and Chemistry or Biochemistry major, or permission of Department. Not open to students with credit for 2520 (253), or 2920H.

Honors introduction to structure, nomenclature, physical properties, preparation and reactions of alkanes, alkenes, alkynes, alcohols, ethers, epoxides, aldehydes and ketones, including stereochemistry, acids, bases, and reaction mechanisms. Prereq: 1220 (123), 1620 (163), or 1920H (203H); Honors program or permission of department or instructor. Not open to students with credit for 2510, 2610, or 252H.

Continuation from 2910H, including aromatic systems, carboxylic acids, carboxylic acid derivatives, amines, carbon-carbon bond-forming reactions, polymers, carbohydrates and amino acids. Prereq: Honors standing, and 2910H (252H) or 252; or permission of department or instructor. Not open to students with credit for 2520, 2620, or 253H.

The course focus is on the science and public policy that govern drug development. The principles of chemistry and biochemistry are applied to research and development of drug therapeutics. The drug approval process of drug safety, toxicity, and clinical trials will focus on pharmaceutical industry challenges of drug affordability, safety, and drug development impact on global public health. Prereq: Biology 1113.xx; Chem 1220, 1250, 1620 or 1920H. Not open to students with credit for PHR 3301. Cross-listed in PHR.

Introduction to the principles of inorganic structure and bonding, including molecular symmetry, atomic structure, ionic bonding, coordination complexes, magnetic properties, thermodynamics and reactivity, bioinorganic chemistry, and nanoparticles. Prereq: 2520 (253), 2620 (253), or 2920H (253H), or permission of instructor. Not open to students with credit for 652.

This course covers quantum mechanics and spectroscopy, beginning with an overview of classical mechanics and the historical origins of quantum theory. Basic quantum mechanics problems including the particle in a box, rigid rotor, harmonic oscillator, and hydrogen atom will be discussed, leading to a description of chemical bonding and modern computational molecular orbital theory (Hartree-Fock). Prereq: 2210, 2510, 2610, 2910H, or equivalent; and Physics 1201 or 1251; and Math 1152 or 1172. Not open to students with credit for 4300 or Biochem 5721.

Quantum mechanics, spectroscopy, and statistical mechanics. Prereq: 2210, 2510, 2610, 2910H, or equiv, and Physics 1200 or 1250. Prereq or concur: Math 2177, 2255, 2415 or 2173.

Statistical thermodynamics, thermodynamic equilibrium, and chemical kinetics. Prereq: 4300.

Quantitative measurements of chemical phenomena and the application of chemical principles to their interpretation. It is recommended that students complete 1 physical chemistry course before taking this course. Prereq or concur: 4200 (520) or 4300 (530). Not open to students with credit for 541.

Preparation and characterization of inorganic compounds employing a variety of synthetic techniques. Prereq: 3510, or an undergraduate degree with Chem major, or permission of instructor.

Applications of physico-chemical principles to problems in qualitative and quantitative chemical analysis. Prereq or concur: 4200 or 4300; or 520 or 530, and 541.

Laboratory applications of physico-chemical principles to instrumental analysis. Prereq or concur: 4870 (587), or permission of instructor. Not open to students with credit for 588.

Come and explore the natural and unnatural organic molecules involved in neurotransmission. Through the study of synthetic strategies, mechanistic principles, and the structural requirements for biological activity, students will investigate the chemical world of endogenous molecules, pharmaceuticals, and drugs of abuse. Recommended prereqs: Chem 2550, and Biochem 4511 or 5613. Prereq: 2520, 2620, or 2920H, and 2540; or Grad standing; or permission of instructor.

This course provides a practical introduction to the theory and methods of molecular modeling and computational chemistry as it pertains to modeling large biological molecules such as proteins. Hands-on experience will be obtained by all attendees in doing molecular mechanics and modeling dynamic systems (molecular dynamics). Recommended prereq: Biochem 4511. Prereq: 2310, 2510, 2610, or 2910H; or Grad standing; or permission of instructor.

Exploration of the use of spectroscopic techniques for the determination of the structure of organic molecules, including UV/vis, IR, NMR, and MS. Prereq: 2520 (253), 2620 (253), or 2920H (253H), or equiv. Not open to students with credit for 632.

Introduction to synthesis, conformation, and biological importance of carbohydrates and oligosaccharides, including nomenclature, protecting groups, glycoside synthesis, biosynthesis and biology, and NMR methods. Prereq: 2520 (253), 2620, or 2920H (253H), or equiv.

Introduction to fundamental concepts in computational chemistry, including molecular modeling, molecular dynamics, and semi-empirical and ab initio calculations. Prereq: 2520 (253), 2620 (253), or 2920H (253H), or equiv. Not open to students with credit for 644.

This course focuses on the application of NMR Spectroscopy to the structure determination and dynamics of primarily synthetic organic and organometallic products. The practical aspects of acquiring optimized, high-quality data are still beneficial for analysis of these spectra and will be presented as lectures and demonstrations. Prereq: 5420, or permission of instructor.

Introduction to fundamental concepts of nanoscience, exploring strategies for complex assemblies of molecules and developing computational techniques for the investigation of nanotech structures. Prereq: 1220 (123), 1620 (163), or 1920H (203H), and permission of instructor. Not open to students with credit for 611.